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Facts About Celebrex

What Exactly is Gout?

Nearly 80 percent of people who first have symptoms of gout generally feel a burning and excruciating pain in the big toe. With the slow buildup of uric acid in the big toe or other joints—ankle, heel, instep, knee, wrist, elbow, fingers, hand, and even spine—gout can attack one of these bodily junctures at any one time.

If you are a gout sufferer, you are not alone as more than 2 million people endure gout annually in the United States alone. If you are a man in your 40s or 50s (chances are lower for women) with a high proliferation of uric acid that is not properly broken down, minute purines can crystallize in your joints causing a gout attack. If not treated properly, this crystallization abundance could lead to subsequent and serious health complications later.

In addition to medications such as Celebrex, there are natural, diet oriented remedies that are extremely effective when it comes to long term management of Gout.

What is Celebrex?

Although remedies have existed before modern medicine, people today often control symptoms of gout through prescription medication. One medication in particular is Celebrex, a drug categorized as a nonsteroidal anti-inflammatory drug (NSAID), meaning the drug does not include steroids but is used to decrease inflammation and sooth pain; however, this drug is used in treating arthritis, joint pain, menstrual cramps, ankylosing spondylitis and colonic polyps, so though intended for pain relief, it does not rid the body of uric acid waste, the cause of gout.

How Does Celebrex Work?

Celebrex is known to be a COX-2 inhibitor—blocking enzymes, thus lowering concentrations of prostaglandins (prostanoids) or cyclooxygenase 2—oftentimes used to reduce pain and inflammation in older adults with osteoarthritis (OA) and rheumatoid arthritis (RA). The former ailment caused from cartilage breakdown resulting in pain and stiffness, with the latter being more common in women than men, causing joint lining inflammation and resulting in stiffness, swelling, and redness. Because of the hindrance in enzymes, Celebrex helps reduce the common manifestations of swelling, inflammation and tenderness associated with gout as well.

What is the History of Celebrex?

Celebrex was first approved by the FDA in the U.S. in 1998 following a 12-month clinical trial involving 8, 059 patients, paid for in full by a manufacturing Searle division of Pfizer Pharmaceuticals. With the discovery of the -1 and -2 forms of cyclooxygenase in the early 1990s, Pfizer created Celebrex as a substitute pain reliever that was thought to have less gastrointestinal side effects frequently associated with other NSAIDs, such as ibuprofen or naproxen.

What are Common Celebrex Side Effects?

Though a similar drug Vioxx was recently pulled from shelves, Celebrex has remained in wide usage throughout the U.S. and Canada. However, recent claims by corroborating users suggest that taking Celebrex might have adverse affects to the cardiovascular system. The Celebrex warning itself suggests an increase in the chance of heart attack or stroke that can lead to death, with further warnings about serious skin reactions or stomach and intestinal problems such as bleeding and ulcers. In fact, on November 4, 2004 a suit was filed against Celebrex in Canada because of cardiovascular side effects, while on November 28, 2004 the Canada Adverse Drug Reaction Monitoring Program confirmed 14 Celebrex related deaths.

The FDA in the U.S. recently issued other warnings associated with Celebrex if the drug is used for an extended period of time. The National Cancer Institute claims that the chance of heart attack increases with individuals who take 400-800 mg of Celebrex daily. Moreover, the FDA links Celebrex to bleeding stomach ulcers, kidney failure, liver damage and water retention. Other claims include diarrhea, dizziness, gas, nausea, headache, indigestion and intestinal pain, with other warnings against mixing alcohol consumption and the Celebrex drug. In the future, the drug may be banned as increasing cases of such aforesaid damages accrue.

What is Celebrex Dosage and Cost?

Though not pulled from shelves, doctors prescribe Celebrex on a case-by-case basis.

The prescribed amount is often 100 mg twice a day or 200 mg as a single dosage. The dosage varies with each examination; however, some dosage exceeds 400 mg twice daily, or up to 800 mg as a single daily dose. The cost of Celebrex varies by state and country: Branded Celebrex can cost between $200-400 USD per 50 pills of 100 mg, while the generic offshoot can cost anywhere from $25-$200 dollars for 30 pills of 100 mg, not including doctor’s fees and other expenses.

If you are looking for an easy, natural alternative to taking Celebrex, Click Here

Pfizer Pharmaceuticals is the manufacturer and distributor of Celebrex (celecoxib capsules) brand medication.
We are not associated with the Pfizer Pharmaceuticals or any of its affiliates.
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